Cherohala Skyway (TN, NC)
The Road: A 43-mile National Scenic Byway in Tennessee and North Carolina whose name is derived from the two national forests it bisects: the Cherokee and the Nantahala.
The Ride: Panoramic views of the Unicoi Mountains, the Citico Creek Wilderness, and the Joyce Kilmer Memorial Forest. Bonus: the Skyway links to Tail of the Dragon.
When To Go: Spring to fall is primetime for this ride, though summer's peak tourist traffic can be pesky.