Mind the blowout.
Professional teams are happy to walk away with a win, whether it's by one point or 20. Some college teams, though, will run up the score so they can cover a spread of 25 or 30 points much more easily. Research who does it – Urban Meyer at Ohio State, say – and don't bet on anyone who hasn't been called out in the national press for their hubris. Gamblers will have to spend less time looking at this after this season, when a playoff structure will replace the arcane bowl system, making one point wins as valued as blowouts.