Surrounded by Siskiyou National Forest, one of the country's wildest woods, Oregon's Rogue River Valley offers high-quality wine sampling without a snobby aftertaste. Think tiny vineyards pouring award-winning syrahs and red Bordeaux varietals among thick stands of old-growth firs. Still less known than pinot-heavy Willamette Valley, this area is filled with the sort of woodsy eccentrics who dismiss Sonoma as a retirement community.
Head to the manageable Applegate Valley, which has about 18 wineries that do tastings. Must-tries are the syrah at Valley View, the zinfandel at Troon, and the red blends at Wooldridge Creek. From Wooldridge, you can hike the well-groomed Felton Trail toward more vineyards. For a truly remote experience amid old-growth Douglas firs, hike or bike along Briggs Creek trail, part of a 500-mile network of paths through the national forest. If you're looking to do the tour at pace, grab bikes and maps at the Siskiyou Cyclery.
More information: Fly into Medford, Oregon, and drive to the rustic Weasku Inn, in Grants Pass, where cabin-style rooms are available from $200 a night.