Richmond, 1991
Credit: Doug Mills / Getty Images

The Spiders were no strangers to big tournament wins, having pulled off upsets in 1984 and 1988. But they made history in '91 by becoming the first No. 15 seed to beat a No. 2 seed, building a 10-point second-half lead over Big East champion Syracuse and holding on as a national TV audience got switched to see this stunner in the making.