Monk Fruit
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Derived from antioxidant-rich fruits first cultivated by Buddhist monks nearly 800 years ago, this natural option seems too good to be true: it's zero-calorie, non-glycemic, free of aftertaste, and has anti-inflammatory benefits. Just be sure to avoid products like Splenda's "Nectresse," which is marketed as monk fruit sweetener but contains added sugar and molasses.

Best uses: Use the granular sweetener as a replacement for syrup in cold drinks and cocktails – it dissolves instantly. It's also 300 times sweeter than sugar, so you only need a pinch.