4. 12 Monkeys (1995)
Based on the French short-film La Jetee, 12 Monkeys stars Bruce Willis as a prisoner selected to go back in time from 2027 (there's that year again) to the mid-'90s to collect information on a virus that has wiped out almost the entire human race. Despite the fanciful time-travel aspect, Martin says a virus nearly killing us off is historically and factually-based. "The virus is the eradicator of choice, which would be one the easiest and most effective methods of killing the 7.1 billion people who are now on Earth. It's hard, and expensive, to do a WW3 or nuclear attack, or to collapse an economy or terrorist attacks. The virus just does it itself, all you have to do is release it. You’ve got the Black Plague, the Spanish Flu — these major viruses that wiped out two-thirds or three-fourths of the worlds population. I don't think it'd be hard at all to take a virus on a plane and spread it around the world. There are viruses from eight years ago that are called global killers that they didn't tell us had escaped from these labs. This has happened several times. It's not a question of when this would happen — it has happened. If somebody had access to this, they could release it. They would have to make the virus airborne, so that it lives and thrives in the nostril cavity of animal or man. So we could definitely see it."