50 Cent (lost 54 pounds)
Credit: Everett

What sucks for Curtis Jackson is that the picture he posted of himself from the set of Things Fall Apart (he played a football played with cancer) attracted more attention than the film, which he wrote. "I lost 54 pounds for it," said the rapper-actor, who ended up a gaunt 160 after nine weeks on a liquid diet and running for three hours on a treadmill daily. "I was starving."

The Bottom Line:
He could have ended up hospitalized himself: Due to a likely combination of low blood pressure and low blood sugar, the rapper-actor was at risk for passing out. As for his diet, Bacon notes, "Sure, he's losing weight but he's not providing his body with valuable nutrients: How helpful can that be?"