The Vendue, Charleston, South Carolina
Two boutique hotels housed in historic warehouses in Charleston's trendy French Quarter are collectively known as The Vendue. And the two of you will have a collective good time here, surrounded by spectacular international art (there are several exhibitions held at the hotel throughout the year) and with perks like complimentary bikes at the ready. "It's an art hotel that embodies the spirit and history of Charleston while also providing a charming and romantic place in which to hole up for the weekend," says Tennessee-based travel writer Kristin Luna. Cocktails at the rooftop bar come with views of the harbor and the city's iconic Ravenel Bridge.