A lethal dose — the size of a pin head — of the puffer fish (Fugu) contains tetrodotoxin, a neurotoxin 1,200 times deadlier than cyanide. This means one fish can kill around 30 people. The Fugu skin, and some organs like the ovaries and liver, are the source of a paralyzing death when not prepared correctly. Because of the high stakes, chefs usually undergo two to three years of training to obtain a fugu-preparing license, and having fugu in a restaurant could run you $50 or more in Japan. This Japanese delicacy comes in around 40 kinds of fugu fish, and around 10,000 tons of the fish are consumed in Japan every year.
Where to Try it Safely Prepared: Hoshinoya in Kyoto, Japan, prepares a blowfish sashimi.