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Earlier this year, I decided to give MK-677 (Ibutamoren) a try.
MK-677 is an oral “research chemical” that increases growth hormone levels and insulin-like growth factor-1.
Some people say it will help:
- Build muscle
- Boost energy
- Improve sleep
- Increase strength
- Preserve muscle while dieting
- Improve skin
It’s meant to be great for anti-aging and improving your physique.
But is MK-677 safe, and does it actually work?
Carry on reading my MK-677 review to find out!
What is MK-677 aka Ibutamoren?
MK-677 is the code name for Ibutamoren.
Ibutamoren is a research chemical that mimics ghrelin, a naturally occurring hormone found predominantly in the digestive system.
Ghrelin controls appetite and helps regulate growth hormone secretion.
Ibutamoren acts as an agonist of the ghrelin receptor, which means it stimulates the body to produce and secrete more growth hormone.
MK-677 is classified by the FDA as an “Investigational New Drug” and is not approved for human use.
So, what benefits does it offer?
MK-677 is a research chemical that has not been approved for human use; however, many studies and clinical trials show its effects on animals and humans.
Here’s what you need to know.
High Oral Bioavailability
The main benefit of MK-677 is its high oral bioavailability, which means it can be taken orally (mixed with water) and doesn’t need to be injected.
It works identically to the growth hormone release peptide GHRP-6 yet has a much higher bioavailability and a much longer serum half-life (24 hours).
In other words, you can take Mk-677 once a day and don’t have to worry about injections or complicated dosing schedules.
Safer Than Growth Hormone Therapy
The other main benefit of MK-677 is that it appears to be much safer than injectable growth hormone.
Injectable growth hormone increases GH and IGF-1 way above normal, which shuts down the body’s natural growth hormone production and increases the risk of side effects like cancer.
MK-677 is different. It merely stimulates the body to produce more GH and IGF-1 without taking them to supraphysiological levels.
The main reason why athletes and bodybuilders are interested in MK-677 is that some studies have shown that it may offer some of the same anabolic benefits as growth hormone therapy.
- This two-month study involving obese test subjects found that MK-677 increased growth hormone secretion, fat-free mass, and energy expenditure, Men who received MK-677 put on 3 kg more muscle than those who got the placebo.
- This 14-day trial found that MK-677 helped preserve lean muscle mass in test subjects while dieting.
Another benefit of MK-677 is that it appears to improve sleep.
This study found that test subjects who took MK-677 experienced a 20% increase in Rapid Eye Movement (REM) sleep and a 50% increase in stage 4 sleep.
On the surface, this research all sounds great. Ibutamoren can be taken once a day, doesn’t need to be injected, and has been shown to help test subjects gain muscle and sleep better.
But are there any side effects?
MK-677 Side Effects
All the studies I referred to above indicate that MK-677 is well tolerated by test subjects and doesn’t cause serious side effects.
They were all very short and involved patients with health concerns, like children with a growth hormone deficiency or adults suffering from wasting conditions or obesity.
Unfortunately, there haven’t been any long-term studies that have examined the safety of MK-677 in healthy individuals.
Also, MK-677 hasn’t yet passed a single Phase 2 clinical trial.
The only known Phase 2 trial, conducted by Lumos Pharma, was suspended due to safety concerns that it increased blood glucose levels and decreased insulin sensitivity.
How is MK-677 dosed?
MK-677 is a research chemical and doesn’t have a “safe” dosage.
All I could do was look at trials and studies to see how researchers had administered in the past.
For example, in this sleep study involving MK-677, test subjects were given 25mg daily, so I decided to take that.
Here’s my experience.
My Experience With MK-677
I planned to take 25mg of MK-677 per day for three months.
Here’s what happened:
- The most noticeable effect of taking MK-677 was that it helped me sleep better. After a few days, I was sleeping like a baby. I hadn’t slept that well in years, and it changed everything. I woke up feeling rested and was far more productive during the day.
- Then, I noticed that I was recovering from workouts much faster. The soreness I usually feel after a heavy chest or leg day didn’t last as long. It helped me stick to my training schedule.
- My workouts were more intense, and I started getting great pumps.
- After a few weeks, I noticed a massive difference in the quality of my skin. My wrinkles were noticeably smoother, and my girlfriend told me I was looking younger and healthier.
After using it for 6 weeks, I was pretty impressed with MK-677.
I had more energy, I was sleeping better, my workouts were going great, and I was looking and feeling younger and gaining muscle.
But then I started noticing some negative side effects I didn’t like, such as bloating, dizziness, muscle cramps, and difficulty getting an erection.
I wasn’t sure whether it was down to the MK-677, so I stopped taking it, and within 48 hours, I was back to normal and can only put it down to using Ibutamoren.
Should You Buy MK-677?
Although I found it pretty good initially, I wouldn’t recommend MK-677.
After reading more user experiences posted online, it seems like side effects are very common with Ibutamoren.
And for building muscle, it’s not that great. If you want to build muscle, give this a try instead. It’s amazing.
I Found Something Better Than MK-677!
After getting some positive results using MK-677 and having to quit using it, I started Googling to see if there’s a way to reduce the risk of side effects.
And that’s when I found a new product called Ibuta-677 by a company called Crazy Bulk.
Crazy Bulk says that Ibuta-677 will provide the same benefits as MK-677 but without the negative side effects.
So I decided to buy a bottle and give it a try:
After using it for 30 days, I was seriously impressed. I felt like I was using real MK-677 with no side effects.
I began to experience:
- More energy
- Improved focus
- Better sleep
- Amazing workouts
- Clearer and younger-looking skin
- Muscle gains
- Faster recovery
If you’re thinking of using MK-677, then I’d recommend trying Ibuta-677 first because, in my experience, it gives the same benefits with no side effects.
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